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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $146.00 |
About This Item
Empirical Formula (Hill Notation):
C18H22N4OS · HCl
CAS Number:
Molecular Weight:
378.92
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 5 mg/mL, clear
storage temp.
2-8°C
SMILES string
Cl.CN(C1CCCCC1)C(=O)c2sc3nc4ccc(N)cc4n3c2C
InChI
1S/C18H22N4OS.ClH/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18;/h8-10,13H,3-7,19H2,1-2H3;1H
InChI key
WYTJVUVCSUWZTH-UHFFFAOYSA-N
Biochem/physiol Actions
YM-298198 is a selective, noncompetitive mGlu1 receptor antagonist.
YM-298198 is an orally active, noncompetitive mGlu1 receptor antagonist. The compound inhibits glutamate-induced inositol phosphate production in NIH3T3 cells (IC50 = 16 nM). YM-298198 displays analgesic and antinociceptive properties in vivo.
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description solid | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form solid | form powder | form powder |
| assay ≥98% (HPLC) | assay - | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: 5 mg/mL, clear | solubility H2O: soluble | solubility H2O: ≥10 mg/mL | solubility DMSO: ≥10 mg/mL at warmed to 60 °C |
| storage condition desiccated | storage condition - | storage condition desiccated | storage condition - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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