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SML0621

WZB117

≥98% (HPLC)

Synonym(s):

3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate), 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$136.00
$115.60
25 mg

Available to ship TODAYfromMILWAUKEE

$574.00

About This Item

Empirical Formula (Hill Notation):
C20H13FO6
CAS Number:
Molecular Weight:
368.31
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$115.60

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Product Name

WZB-117, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1=CC=CC(O)=C1)OC2=C(F)C=CC=C2OC(C3=CC(O)=CC=C3)=O

InChI

1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H

InChI key

FRSWCCBXIHFKKY-UHFFFAOYSA-N

Application

WZB-117 has been used to study its tumor initiating ability in cancer stem cells. It has also been used to study the effect of glucose antagonists on 2-NBDG (2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose) uptake.

Biochem/physiol Actions

WBZ 117 is an inhibitor of basal glucose transport in H1299 lung and other cancer cells.
WBZ 117 is an inhibitor of basal glucose transport.
WZB-117 is an irreversible inhibitor. In cancer cells, WZB-117 prevents cell growth by stimulating apoptosis in any glucose concentration. It targets self-renewal and tumor-initiating capacity in cancer stem cells.

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This Item
SML1467400036SML1171
description

≥98% (HPLC)

description

≥98% (HPLC)

description

The Glucose Transporter Inhibitor IV, WZB117 controls the biological activity of Glucose Transporter.

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 25 mg/mL, clear

solubility

ethanol: 100 mg/mL

solubility

DMSO: 0.5 mg/mL, clear (warmed)

storage condition

desiccated

storage condition

-

storage condition

OK to freeze, desiccated, protect from light

storage condition

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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