SML0639
Ro 11-1464
≥98% (HPLC)
Synonym(s):
9-Methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
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About This Item
Empirical Formula (Hill Notation):
C15H12N4S
CAS Number:
Molecular Weight:
280.35
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Ro 11-1464 induces the hepatic expression of apoA-1 and leads to increased levels of apoA-1 in the plasma. Treatment of human apoA-1 transgenic mice with Ro 11-1464 resulted in a three-fold increase in hapoA-1 mRNA in the liver, and a two-fold increase in plama apoA-1levels. The compound causes a significant decrease in plama lipids and enhances reverse cholesterol transport.
Ro 11-1464 induces the hepatic expression of apoA-1.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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