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SML0710

DDRI-18

≥98% (HPLC)

Synonym(s):

3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine

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Size/SKUAvailabilityPrice
5 mg
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$92.10

About This Item

Empirical Formula (Hill Notation):
C26H20N6
CAS Number:
Molecular Weight:
416.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$92.10


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL

storage temp.

2-8°C

SMILES string

NC1=CC=CC(C(N2)=NC(C=C3)=C2C=C3C4=CC5=C(C=C4)N=C(N5)C6=CC(N)=CC=C6)=C1

InChI

1S/C26H20N6/c27-19-5-1-3-17(11-19)25-29-21-9-7-15(13-23(21)31-25)16-8-10-22-24(14-16)32-26(30-22)18-4-2-6-20(28)12-18/h1-14H,27-28H2,(H,29,31)(H,30,32)

InChI key

QROWVLFOWUYBIG-UHFFFAOYSA-N

Biochem/physiol Actions

DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin.
DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair.

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This Item
SML1274CB_96090512667218
vibrant-m

Ri-1

description

≥98% (HPLC)

description

≥98% (HPLC)

description

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 96090512, human blood, Lymphoblastoid

description

97%

form

powder

form

powder

form

-

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

97%

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−196°C

storage temp.

-

solubility

DMSO: 10 mg/mL

solubility

DMSO: 10 mg/mL, clear

solubility

-

solubility

-

color

white to beige

color

yellow to orange

color

-

color

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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