SML0730
PCNA-I1
≥98% (HPLC)
Synonym(s):
N-(3-Methylthiophene-2-carboxylic acid)-N′-[(3-hydroxy-2-naphthalenyl)methylene]hydrazide
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $119.00 |
About This Item
Empirical Formula (Hill Notation):
C17H14N2O2S
CAS Number:
Molecular Weight:
310.37
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
PCNA-I1 is a PCNA inhibitor.
PCNA-I1 is a small molecule PCNA inhibitor that selectively binds to PCNA trimers and reduces the association of PCNA with chromatin. PCNA-I1 induces S and G2/M phase cell cycle arrest in tumor cells with greater efficacy than non-transformed cells.
Proliferating cell nuclear antigen-l1 (PCNA) is a member of the scaffold B class. It acts as a linker at the monomer-monomer interface. PCNA-I1 has the ability to block the development of primary cultures of bone marrow mesenchymal stem cells, endothelial cells, lymphocytes, mammary epithelial cells and prostate epithelial cells.
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description IgG fraction of antiserum | description - | description clone 1G7, purified immunoglobulin, buffered aqueous solution |
| form powder | form buffered aqueous solution | form liquid | form buffered aqueous solution |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 10 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.