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SML0834

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside

≥98% (HPLC)

Synonym(s):

2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside, EH-201, THSG, Tetrahydroxystilbene glucoside

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Size/SKUAvailabilityPrice
5 mg
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$114.00
25 mg
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$314.00

About This Item

Empirical Formula (Hill Notation):
C20H22O9
CAS Number:
Molecular Weight:
406.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$114.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to brown

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)Oc2c(cc(cc2\C=C\c3ccc(cc3)O)O)O

InChI

1S/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/m1/s1

InChI key

JAYVHSBYKLLDJC-DSNJPTTOSA-N

General description

2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol.

Biochem/physiol Actions

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO.
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models.
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside (THSG) elicits anti-inflammatory, antioxidative and anti-atherosclerotic functionality. It also provides protection against cytotoxicity in neuroblastoma cells induced by 1-methyl-4-phenyl pyridium (MPP+) as well as MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson′s disease. By its antioxidative functionality, it blocks lipid peroxidation in Alzheimer′s disease model. In ligature-induced periodontitis, THSG inhibits inflammation.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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1 of 1

This Item
G7548PHL826661651654
description

≥98% (HPLC)

description

≥96% (HPLC)

description

phyproof® Reference Substance

description

United States Pharmacopeia (USP) Reference Standard

form

powder

form

powder

form

solid

form

-

assay

≥98% (HPLC)

assay

≥96% (HPLC)

assay

≥95.0% (HPLC)

assay

-

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

solubility

H2O: 5 mg/mL, clear (warmed)

solubility

DMSO: ≥20 mg/mL

solubility

-

solubility

-

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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