SML0910
TC3.6
≥98% (HPLC)
Synonym(s):
3-Phenyl-2,4(1H,3H)-quinazolinedithione
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C14H10N2S2
CAS Number:
Molecular Weight:
270.37
UNSPSC Code:
41106305
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
light orange to dark orange
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
Sc1[n]([c](c3c(n1)cccc3)=S)c2ccccc2
InChI key
DJJOAJCVIYRELX-UHFFFAOYSA-N
Biochem/physiol Actions
TC3.6 is a PDE7 selective inhibitor (IC50 = 1.04 μM). In an Experimental Autoimmune Encephalomyelitis (EAE) murine model, TC3.6 reduced levels of IL-17, blocked infiltration of immune cells into the CNS and elevated levels of the Treg marker Foxp3. TC3.6 also enhances survival and differentiation of oligodendrocyte precursor cells.
TC3.6 is a PDE7 selective inhibitor.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.