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SML1139

Rostafuroxin

≥98% (HPLC)

Synonym(s):

(3,5,14)-21,23-epoxy24-Norchola-20,22-diene-3,14,17-triol, PST 2238

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Size/SKUAvailabilityPrice
5 mg
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$164.00
25 mg
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$445.00

About This Item

Empirical Formula (Hill Notation):
C23H34O4
CAS Number:
Molecular Weight:
374.51
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$164.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

[o]1cc(cc1)[C@@]2([C@@]3([C@@]([C@H]4[C@@H]([C@@]5([C@@H](C[C@H](CC5)O)CC4)C)CC3)(CC2)O)C)O

InChI

1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1

InChI key

AEAPORIZZWBIEX-DTBDINHYSA-N

Biochem/physiol Actions

Rostafuroxin is a Na-K ATPase; Ouabain antagonist.
Rostafuroxin is a digitoxygenin derivative that selectively antagonizes the effects of endogenous ouabain on the Na+,K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin lowers blood pressure (BP) in animal models of hypertension.
Rostafuroxin is a derivative of digitoxigenin. It protects animal models against podocyte lesions and proteinuria by counteracting mutant β-adducin and ouabain-mediated effects.

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This Item
M4074SML0212SML1468
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 5 mg/mL, clear (warmed)

color

white to beige

color

white to off-white

color

white to tan

color

white to beige


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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