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SML1174

ML120B

≥98% (HPLC)

Synonym(s):

MLN120B, N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methyl-3-pyridinecarboxamide

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship TODAYfromMILWAUKEE

$153.00

About This Item

Empirical Formula (Hill Notation):
C19H15ClN4O2
CAS Number:
Molecular Weight:
366.80
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$153.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1cc2c([nH]c4c2ccnc4)c(c1OC)NC(=O)c3c(nccc3)C

InChI

1S/C19H15ClN4O2/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16/h3-9,23H,1-2H3,(H,24,25)

InChI key

ZNOLRTPMNMPLHY-UHFFFAOYSA-N

Biochem/physiol Actions

ML120B is a potent inhibitor of IKK-2 (IC50 = 60 nM). ML120B is orally bioavailable, and inhibits paw swelling, bone and cartilage degradation, and weight loss in rat adjuvant-induced arthritis.
ML120B is a potent inhibitor of IKK-2.

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This Item
SML1225L6670SML0044
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC), powder

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: ≥10 mg/mL

color

white to beige

color

white to pink

color

white to tan

color

white to tan


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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