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SML1193

SU1498

≥98% (HPLC)

Synonym(s):

(2E)-2-Cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-2-propenamide, (E)-N-(3-Phenylpropyl)-cyano-3,5-diisopropyl-4-hydroxycinnamamide, AG-1498, SU 1498, Tyrphostin SU 1498, Tyrphostin SU1498

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$122.40
25 mg

Available to ship TODAYfromMILWAUKEE

$574.00

About This Item

Empirical Formula (Hill Notation):
C25H30N2O2
CAS Number:
Molecular Weight:
390.52
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$122.40

List Price$144.00Save 15%

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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

−20°C

SMILES string

N(CCCc2ccccc2)C(=O)\C(=C\c1cc(c(c(c1)C(C)C)O)C(C)C)\C#N

InChI

1S/C25H30N2O2/c1-17(2)22-14-20(15-23(18(3)4)24(22)28)13-21(16-26)25(29)27-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-15,17-18,28H,8,11-12H2,1-4H3,(H,27,29)/b21-13+

InChI key

JANPYFTYAGTSIN-FYJGNVAPSA-N

Biochem/physiol Actions

SU1498 is a potent and selective inhibitor of the VEGFR2 receptor kinase, Flk-1 with an IC50 value of 700 nM. SU1498 is a very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase with IC50 values > 50 μM. SU1498 has been used to study the role of VEGFR2 (Flk-1) in a variety of biological activities including angiogenesis, tumor growth inhibition, and stem cell proliferation.
SU1498 is a potent and selective inhibitor of the VEGFR2 receptor kinase, Flk-1.

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This Item
SML1603L6920SML0936
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC), powder

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 25 mg/mL, clear

solubility

DMSO: ≥19 mg/mL

solubility

DMSO: 5 mg/mL, clear (warmed)

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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