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SML1285

Febuxostat

98.5-102.0% (dry basis), powder, xanthine oxidase inhibitor

Synonym(s):

2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid, Adenuric, Atenuri, Uloric

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Size/SKUAvailabilityPrice
1 g

Available to ship TODAYfromMILWAUKEE

$228.00

About This Item

Empirical Formula (Hill Notation):
C16H16N2O3S
CAS Number:
Molecular Weight:
316.37
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
98.5-102.0%
Form:
powder

$228.00


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Product Name

Febuxostat, 98.5-102.0%

Quality Segment

assay

98.5-102.0%

form

powder

storage temp.

2-8°C

SMILES string

CC(C)COC1=C(C#N)C=C(C2=NC(C)=C(C(O)=O)S2)C=C1

InChI

1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)

InChI key

BQSJTQLCZDPROO-UHFFFAOYSA-N

General description

Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.

Biochem/physiol Actions

Febuxostat is a potent non-purine xanithine oxidase inhibitor.
Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.

Disclaimer

Freely soluble in N,N-dimethyl formamide, Soluble in dimethyl sulfoxide, sparingly soluble in ethanol or trichloromethane, slightly soluble in methanol, practically insoluble in water

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description

98.5-102.0%

description

SB 202190, CAS 152121-30-7, is a potent, reversible, competitive inhibitor of p38. Inhibits p38 phosphorylation of myelin basic protein. Blocks the activity of p38β (Ki = 16 nM; IC50 = 350 nM).

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The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.

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assay

98.5-102.0%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

powder

form

solid

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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