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SML1310

NSC756093

≥98% (HPLC)

Synonym(s):

4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl-furo[3,4-b]quinolin-1(3H)-one, 4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$111.00
$94.35
25 mg

Available to ship TODAYfromMILWAUKEE

$295.00
$250.75

About This Item

Empirical Formula (Hill Notation):
C20H19NO4
CAS Number:
Molecular Weight:
337.37
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$94.35

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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

OCCN1C2=C(C(OC2)=O)C(C3=CC=CC=C3)C4=C1C=C(OC)C=C4

InChI

1S/C20H19NO4/c1-24-14-7-8-15-16(11-14)21(9-10-22)17-12-25-20(23)19(17)18(15)13-5-3-2-4-6-13/h2-8,11,18,22H,9-10,12H2,1H3

InChI key

SMEJQLRLHKWIFV-UHFFFAOYSA-N

Biochem/physiol Actions

NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction that inhibits proliferation of paclitaxel resistant cancer cells. Apparently, NSC756093 stabilizes a conformation of GBP1 not suitable for binding to PIM1.
NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction.

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This Item
SML0376B7438SML2221
description

≥98% (HPLC)

description

≥98% (HPLC)

description

>98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

>98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: >2 mg/mL (warmed)

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

light yellow to light brown

color

white to off-white

color

white to beige


pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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