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SML1467

ASP7663

≥98% (HPLC)

Synonym(s):

(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid, (E)-[7-Fluoro-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetic acid

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Size/SKUAvailabilityPrice
5 mg
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$144.00
25 mg

Available to ship TODAYfromMILWAUKEE

$435.00

About This Item

Empirical Formula (Hill Notation):
C14H14FNO3
CAS Number:
Molecular Weight:
263.26
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$144.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 25 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O

InChI

1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+

InChI key

RCVZUIGCNAAMIC-UXBLZVDNSA-N

Biochem/physiol Actions

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.
ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1).

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This Item
SML1897X3629SML2074
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 25 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: >40 mg/mL

solubility

-

color

light orange to dark orange

color

, yellow to light brown

color

orange

color

red-brown


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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