The solubility of the product in DMSO is 20 mg/mL and the solution is clear. Additionally, it exhibits slight solubility in DMSO, ethanol, and methanol.
SML1523
Estetrol
≥98% (HPLC), selective estrogen receptor modulator, powder
Synonym(s):
15α-Hydroxyestriol, 3,15α,16α,17β-Tetrahydroxyestra-1,3,5(10)-triene, E4, Estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol, Oestetrol
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Estimated to ship TODAYfromMILWAUKEE | $241.00 |
25 mg | Estimated to ship TODAYfromMILWAUKEE | $958.00 $814.30 |
About This Item
Empirical Formula (Hill Notation):
C18H24O4
CAS Number:
Molecular Weight:
304.38
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
Estetrol, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
[H][C@@]12CCC3=CC(O)=CC=C3[C@@]1([H])CC[C@@]4(C)[C@@]2([H])[C@@H](O)[C@@H](O)[C@@H]4O
InChI
1S/C18H24O4/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3/t12-,13-,14-,15-,16-,17+,18+/m1/s1
InChI key
AJIPIJNNOJSSQC-NYLIRDPKSA-N
General description
Biochem/physiol Actions
Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver.
Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver. Estetrol is a selective estrogen receptor modulator (SERM) with potent estrogenic effects on vaginal mucosa, bone and brain, neutral effect on liver, and anti-estrogen effects on breast tissue. Estetrol has higher affinity for ERα over ERβ. Estetrol is being studied for its potential as a contraceptive, a drug for meopausal symptoms, and an anticancer agent.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥97% | description United States Pharmacopeia (USP) Reference Standard | description ≥98% (TLC) |
| form powder | form powder | form - | form powder |
| assay ≥98% (HPLC) | assay ≥97% | assay - | assay ≥98% (TLC) |
| Quality Level 100 | Quality Level 200 | Quality Level - | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. - | storage temp. room temp |
| solubility DMSO: 20 mg/mL, clear | solubility ethanol: water (1:1): 10 mg/mL, clear to very slightly hazy, colorless | solubility - | solubility methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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