Skip to Content
MilliporeSigma

Skip To

SML1533

(±)-Marinopyrrole A

≥95% (HPLC)

Synonym(s):

(±)-Maritoclax, 1,1′-(4,4′,5,5′-Tetrachloro[1,3′-bi-1H-pyrrole]-2,2′-diyl)bis[1-(2-hydroxyphenyl)-methanone

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
25 mg
Check Cart for Availability
$660.00
$561.00

About This Item

Empirical Formula (Hill Notation):
C22H12Cl4N2O4
CAS Number:
Molecular Weight:
510.15
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder

$561.00

List Price$660.00Save 15%
Web-Only Promotion

Check Cart for Availability

Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥95% (HPLC)

form

powder

color

light yellow to dark yellow

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1[n](c(cc1Cl)C(=O)c4c(cccc4)O)c2c([nH]c(c2Cl)Cl)C(=O)c3c(cccc3)O

InChI

1S/C22H12Cl4N2O4/c23-12-9-13(19(31)10-5-1-3-7-14(10)29)28(22(12)26)18-16(24)21(25)27-17(18)20(32)11-6-2-4-8-15(11)30/h1-9,27,29-30H

InChI key

QYPJBTMRYKRTFG-UHFFFAOYSA-N

General description

Marinopyrrole A (Maritoclax) is a member of phenolic 1,3′-bipyrroles family targeting actin group.

Biochem/physiol Actions

Marinopyrrole A (Maritoclax) is a potent and selective inhibitor of Bcl-2 family member Mcl-1, originally isolated from marine streptomycetes for its antimicrobial activity against methicillin-resistant Staphylococcus aureus. Marinopyrrole A directly binds to Mcl-1 and targets it for proteasomal degradation. Marinopyrrole A induced apoptosis in Mcl-1-dependent cancer cells and sensitized cancer cells to ABT-737.
Marinopyrrole A (Maritoclax) is a potent and selective inhibitor of Bcl-2 family member Mcl-1; antibiotic.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
15156SML3593Y0000202
description

≥95% (HPLC)

description

for TLC derivatization, for the det.of cyanide, ≥98.0%

description

≥95% (HPLC)

description

European Pharmacopoeia (EP) Reference Standard

assay

≥95% (HPLC)

assay

≥98.0% (TLC)

assay

≥95% (HPLC)

assay

-

form

powder

form

powder

form

powder

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

formic acid: 50 mg/mL, clear, yellow

solubility

DMSO: 2 mg/mL, clear

solubility

-

color

light yellow to dark yellow

color

-

color

white to beige

color

-


hcodes

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters