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SML1548

THPN

≥98% (HPLC)

Synonym(s):

1-(2,4,6-Trihydroxyphenyl)-1-nonanone, 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, CID 3063200

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Size/SKUAvailabilityPrice
25 mg
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$459.00

About This Item

Empirical Formula (Hill Notation):
C15H22O4
CAS Number:
Molecular Weight:
266.33
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$459.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 25 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=C(O)C(O)=CC(C(CCCCCCCC)=O)=C1

InChI

1S/C15H22O4/c1-2-3-4-5-6-7-8-12(16)11-9-13(17)15(19)14(18)10-11/h9-10,17-19H,2-8H2,1H3

InChI key

NVFRHTFJDGAFQS-UHFFFAOYSA-N

General description

THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B.

Biochem/physiol Actions

THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma.
THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model.

Other Notes

air sensitive

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This Item
SML1326SML1052SML0340
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 25 mg/mL, clear

solubility

H2O: 10 mg/mL, clear, DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: >10 mg/mL

color

white to beige

color

white to beige

color

white to beige

color

faintly yellow to dark yellow


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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