SML1560
Azoramide
≥98% (HPLC)
Synonym(s):
N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]-butanamide, N-{2-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]ethyl} butanamide
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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Check Cart for Availability | $107.00 |
50 mg | Check Cart for Availability | $435.00 |
About This Item
Empirical Formula (Hill Notation):
C15H17ClN2OS
CAS Number:
Molecular Weight:
308.83
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 30 mg/mL, clear
storage temp.
2-8°C
SMILES string
ClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1
InChI
1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
InChI key
VYBFWKKCWTXCQX-UHFFFAOYSA-N
Biochem/physiol Actions
Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.
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This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description ≥98% (TLC) | description United States Pharmacopeia (USP) Reference Standard |
| form powder | form - | form - |
| assay ≥98% (HPLC) | assay ≥98% (TLC) | assay - |
| Quality Level 100 | Quality Level 200 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 30 mg/mL, clear | solubility - | solubility - |
| color white to beige | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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