Skip to Content
MilliporeSigma

Skip To

SML1599

VR23

≥98% (HPLC)

Synonym(s):

7-Chloro-4-(4-(2,4-dinitrophenylsulfonyl)piperazin-1-yl)quinoline, 7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]-quinoline, VR-23

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg

Estimated to ship onAugust 03, 2026fromMILWAUKEE

$125.00

About This Item

Empirical Formula (Hill Notation):
C19H16ClN5O6S
CAS Number:
Molecular Weight:
477.88
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$125.00


Estimated to ship onAugust 03, 2026Details


Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(N2CCN(CC2)c3c4c(ncc3)cc(cc4)Cl)c1c(cc(cc1)[N+](=O)[O-])[N+](=O)[O-]

InChI

1S/C19H16ClN5O6S/c20-13-1-3-15-16(11-13)21-6-5-17(15)22-7-9-23(10-8-22)32(30,31)19-4-2-14(24(26)27)12-18(19)25(28)29/h1-6,11-12H,7-10H2

InChI key

PDQVZPPIHADUOO-UHFFFAOYSA-N

Biochem/physiol Actions

Potent inhibitor of proteasome that primary targets β2 of the 20S proteasome catalytic subunit
VR23 is a potent inhibitor of proteasome that primary targets β2 of the 20S proteasome catalytic subunit. VR23 selectively induces apoptosis to cancer cells via cyclin E–mediated centrosome amplification. VR23 exhibit little effect on noncancerous cells.
Proteasomes are responsible for the cleavage of peptides in an ATP/ubiquitin-dependent manner.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
R1033SML2350SML0935
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥10 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

color

white to beige

color

light yellow to light tan

color

yellow to brown

color

white to beige


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters