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SML1626

TFCA

≥98% (HPLC)

Synonym(s):

3-(3,4-Dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide, N-(4-Trifluoromethylphenyl) 3,4-dimethoxycinnamamide

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Size/SKUAvailabilityPrice
5 mg
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$101.00
$85.85

About This Item

Empirical Formula (Hill Notation):
C18H16F3NO3
CAS Number:
Molecular Weight:
351.32
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$85.85

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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 25 mg/mL, clear

storage temp.

room temp

SMILES string

O=C(NC1=CC=C(C(F)(F)F)C=C1)/C=C/C2=CC=C(OC)C(OC)=C2

InChI

1S/C18H16F3NO3/c1-24-15-9-3-12(11-16(15)25-2)4-10-17(23)22-14-7-5-13(6-8-14)18(19,20)21/h3-11H,1-2H3,(H,22,23)/b10-4+

InChI key

KFWWXJZNIMFFRO-ONNFQVAWSA-N

Biochem/physiol Actions

TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. Apparently TFCA binds to the LXR? ligand binding domain and induces interaction with NCoR corepressor.
TFCA is a Liver X receptor α (LXRα) antagonist.

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This Item
SML2644F5557D6571
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

-

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

solubility

DMSO: 25 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: >10 mg/mL

solubility

DMSO: ≥20 mg/mL

color

white to beige

color

white to beige

color

white to off-white

color

white to off-white


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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