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SML1884

Mitoglitazone

≥98% (HPLC)

Synonym(s):

5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione, MSDC-0160

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$98.40
$83.64

About This Item

Empirical Formula (Hill Notation):
C19H18N2O4S
CAS Number:
Molecular Weight:
370.42
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$83.64

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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

CCC1=CN=C(C(COC2=CC=C(CC3SC(NC3=O)=O)C=C2)=O)C=C1

InChI

1S/C19H18N2O4S/c1-2-12-5-8-15(20-10-12)16(22)11-25-14-6-3-13(4-7-14)9-17-18(23)21-19(24)26-17/h3-8,10,17H,2,9,11H2,1H3,(H,21,23,24)

InChI key

IRNJSRAGRIZIHD-UHFFFAOYSA-N

Biochem/physiol Actions

MSDC-0160 is an mTOT (mitochondrial target of thiazolidinediones) modulator that targets the mitochondrial pyruvate carrier (MPC), which is a key controller of cellular metabolism. MSDC-0160 is reported to enhance the cells′ ability to handle potentially harmful proteins, which leads to reduced inflammation and less nerve cell death. It has already been in clinical trials for diabetes and Alzheimer′s disease and clinical trials for Parkinson′s Disease are planned.
Mitochondrial pyruvate carrier (MPC) inhibitor

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This Item
R2408E6910SML0896
description

≥98% (HPLC)

description

-

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥10 mg/mL

solubility

DMSO: ≥10 mg/mL

solubility

DMSO: 10 mg/mL, clear

color

white to beige

color

-

color

white to off-white

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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