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SML1910

IC87201

≥98% (HPLC)

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Synonym(s):

2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichloro-phenol, 2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol, IC 87201, IC-87201, Phenol, 2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro-

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$78.70

About This Item

Empirical Formula (Hill Notation):
C13H10Cl2N4O
CAS Number:
Molecular Weight:
309.15
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$78.70

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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to brown

solubility

DMSO: 5 mg/mL, clear

storage temp.

2-8°C

SMILES string

Clc1c(c(cc(c1)Cl)CNc2cc3[nH]nnc3cc2)O

InChI

1S/C13H10Cl2N4O/c14-8-3-7(13(20)10(15)4-8)6-16-9-1-2-11-12(5-9)18-19-17-11/h1-5,16,20H,6H2,(H,17,18,19)

InChI key

QEHVTUCLCBXQIC-UHFFFAOYSA-N

Biochem/physiol Actions

IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures.
IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to NMDA receptor antagonists nNOS/PSD-95 protein-protein interaction inhibitors spared source memory, spatial memory, and motor function in rats.


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3



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