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SML1942

Drotaverine hydrochloride

≥95% (HPLC), powder, PDE inhibitor

Synonym(s):

1-[(3,4-Diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride, 3′,4′,6,7-Tetraethoxy-1-benzylidene-1,2,3,4-tetrahydroisoquinoline hydrochloride, Drotaverin hydrochloride, Tetraspasmin-Lefa

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Size/SKUAvailabilityPrice
10 mg
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$105.00
50 mg
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$424.00

About This Item

Empirical Formula (Hill Notation):
C24H31NO4 · HCl
CAS Number:
Molecular Weight:
433.97
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated

$105.00


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Product Name

Drotaverine hydrochloride, ≥95% (HPLC)

Quality Segment

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CCOC1=CC=C(/C=C2C3=C(CCN/2)C=C(OCC)C(OCC)=C3)C=C1OCC.[H]Cl

InChI

1S/C24H31NO4.ClH/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20;/h9-10,13-16,25H,5-8,11-12H2,1-4H3;1H/b20-13-;

InChI key

JBFLYOLJRKJYNV-MASIZSFYSA-N

Biochem/physiol Actions

A PDE4-selective phosphodiesterase inhibitor and an L-type voltage-dependent calcium channel blocker with in vivo antispasmodic efficacy.
Drotaverine (Drotaverin) is an isoquinoline-based PDE4-selective phosphodiesterase (PDE) inhibitor and an L-type voltage-dependent (voltage-operated) calcium channel (L-VDCC or L-VOCC) blocker that exhibits in vivo antispasmodic efficacy without anticholinergic effects.
It is a benzylisoquinoline derivative. Drotaverine acts as a smooth muscle relaxant.

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This Item
1184118
description

≥95% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard

form

powder

form

-

assay

≥95% (HPLC)

assay

-

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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