SML1949
Synta66
≥98% (HPLC)
Synonym(s):
4-Pyridinecarboxamide, N-(2′,5′-dimethoxy[1,1′-biphenyl]-4-yl)-3-fluoro-, GSK1349571A, N-(2′,5′-Dimethoxy[1,1′-biphenyl]-4-yl)-3-fluoro-4-pyridinecarboxamide, S66, Synta 66, Synta-66
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $121.00 |
25 mg | Available to ship TODAYfromMILWAUKEE | $467.00 |
About This Item
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(NC1=CC=C(C2=C(OC)C=CC(OC)=C2)C=C1)C3=CC=NC=C3F
InChI key
GFEIWXNLDKUWIK-UHFFFAOYSA-N
Application
- as a Ca2+ release-activated calcium (CRAC) channel inhibitor to study its effects on ORAI isoforms
- as an ORAI1 blocker to study its effects on the entry of Ca2+ in chronic lymphocytic leukemia (CLL) B cells
- as a CRAC blocker to study its effects on the influx of Ca2+ by store-operated Ca2+ entry (SOCE) in enamel cells
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC), solid |
| form powder | form powder | form powder | form solid |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| solubility DMSO: 20 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (warmed) | solubility - | solubility DMSO: >5 mg/mL at 60 °C, H2O: insoluble |
| color white to beige | color white to beige | color white to beige | color white |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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