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SML2055

ZD0947

≥98% (HPLC)

Synonym(s):

3-[(4 S)5-Oxo-2-(trifluoromethyl)-1,4,5,6,7,8-hexahydroquinolin-4-yl] benzonitrile, 3-[(4S)-1,4,5,6,7,8-Hexahydro-5-oxo-2-(trifluoromethyl)-4-quinolinyl]-benzonitrile

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Size/SKUAvailabilityPrice
25 mg

Available to ship TODAYfromMILWAUKEE

$397.00
$411.00

About This Item

Empirical Formula (Hill Notation):
C17H13F3N2O
CAS Number:
Molecular Weight:
318.29
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$411.00

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assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -625 to -575°, c = 0.5 in methanol

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1C2=C(NC(C(F)(F)F)=C[C@H]2C3=CC(C#N)=CC=C3)CCC1

InChI

1S/C17H13F3N2O/c18-17(19,20)15-8-12(11-4-1-3-10(7-11)9-21)16-13(22-15)5-2-6-14(16)23/h1,3-4,7-8,12,22H,2,5-6H2/t12-/m0/s1

InChI key

RUVMMEREJMHLOS-LBPRGKRZSA-N

Biochem/physiol Actions

ZD0947 is potent ATP-sensitive K+ channels (KATP channels) opener. ZD0947 is an effective activator of smooth muscle-type KATP channels (SUR2B/Kir6.1 and SUR2B/Kir6.2) but is a partial antagonist of pancreatic-type KATP channels (i.e. SUR1/Kir6.2) and cardiac-type KATP channels (i.e. SUR2A/Kir6.2). ZD0947 potently inhibits carbacho-induced contraction in the strips of human detrusor.
potent ATP-sensitive K+ channels (KATP channels) opener

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This Item
SML2465SML2622SML2419
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

faint yellow to dark orange

color

white to beige

color

white to beige

optical activity

[α]/D -625 to -575°, c = 0.5 in methanol

optical activity

-

optical activity

-

optical activity

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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