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SML2063

Davunetide trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

AL-108, Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln, L-Asparaginyl-L-alanyl-L-prolyl-L-valyl-L-seryl-L-isoleucyl-L-prolyl-L-Glutamine, NAP, NAP peptide, NAPVSIPQ

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Size/SKUAvailabilityPrice
25 mg
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$411.00

About This Item

Empirical Formula (Hill Notation):
C36H60N10O12 · xC2HF3O2
CAS Number:
Molecular Weight:
824.92 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder

$411.00


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assay

≥95% (HPLC)

form

powder

composition

Peptide content, ≥60%

color

white to beige

shipped in

wet ice

storage temp.

−20°C

SMILES string

N2([C@@H](CCC2)C(=O)N[C@@H](CCC(=O)N)C(=O)O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)N)C)C(C)C)CO)[C@H](CC)C

InChI

1S/C36H60N10O12/c1-6-18(4)28(35(56)46-14-8-9-23(46)31(52)41-21(36(57)58)11-12-25(38)48)44-30(51)22(16-47)42-33(54)27(17(2)3)43-32(53)24-10-7-13-45(24)34(55)19(5)40-29(50)20(37)15-26(39)49/h17-24,27-28,47H,6-16,37H2,1-5H3,(H2,38,48)(H2,39,49)(H,40,50)(H,41,52)(H,42,54)(H,43,53)(H,44,51)(H,57,58)/t18-,19-,20-,21-,22-,23-,24-,27-,28-/m0/s1

InChI key

DWLTUUXCVGVRAV-XWRHUKJGSA-N

Biochem/physiol Actions

Davunetide (NAPVSIPQ; NAP) is an eight amino acid peptide identified as the active component of activity-dependent neuroprotective protein (ADNP). It has been found to be neuro-protective at femtomolar concentrations in vitro against the neural toxicity of a wide range of compounds. Davunetide has been investigated for Parkinson′s disease and schizophrenia and in clinical trials for Alzheimner′s Disease, targeting microtubule-tau Interaction.
Neuroprotective peptide; the neuronal tubulin-preferring agent

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This Item
SML3074
description

≥95% (HPLC)

description

≥95% (HPLC)

form

powder

form

film or powder

assay

≥95% (HPLC)

assay

≥95% (HPLC)

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

-

color

white to beige

color

white to off-white

composition

Peptide content, ≥60%

composition

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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