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SML2080

AZD1283

≥98% (HPLC)

Synonym(s):

6-[4-[[(Benzylsulfonyl)amino]carbonyl]piperidin-1-yl]-5-cyano-2-methylnicotinic acid ethyl ester, Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$98.40

About This Item

Empirical Formula (Hill Notation):
C23H26N4O5S
CAS Number:
Molecular Weight:
470.54
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$98.40


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assay

≥98% (HPLC)

form

powder

color

orange to brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C(OCC)C1=CC(C#N)=C(N2CCC(C(NS(CC3=CC=CC=C3)(=O)=O)=O)CC2)N=C1C

InChI

1S/C23H26N4O5S/c1-3-32-23(29)20-13-19(14-24)21(25-16(20)2)27-11-9-18(10-12-27)22(28)26-33(30,31)15-17-7-5-4-6-8-17/h4-8,13,18H,3,9-12,15H2,1-2H3,(H,26,28)

InChI key

NEMHKCNXXRQYRF-UHFFFAOYSA-N

Biochem/physiol Actions

AZD1283 is potent non-nucleotide P2Y12 antagonist with a Kd value of 11 nM. It had good antithrombotic activity, inhibiting ADP-induced platelet aggregation. AZD1283 has been used to study the structure of the human P2Y12 receptor.
Potent P2Y12 antagonist with antithrombotic activity

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SML2121SML2541SML2208
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

orange to brown

color

white to beige

color

white to beige

color

white to beige

AZD1283 100mg P2Y12 receptor study

2-(4-{[2-(5-Chlorothiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-yl]amino}phenyl)acetic acid, A-33 1 mg/mL solution for laboratory use, A-33 PDE4B inhibitor 915082-52-9, A-33 PDE4B inhibitor IC50 value, A-33 chemical structure and properties, A-33 cognitive function improvement study, A-33 compound for TNF-α production inhibition, A-33 for in vitro studies, A-33 intraperitoneal injection study, A-33 lab-grade PDE4B inhibitor, A-33 pharmacological profile and applications, A-33 research chemical for neuroscience applications, A-33 selective PDE4B inhibitor for research, PDE4B inhibitor A-33, Sigma-Aldrich A-33

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Storage Class

11 - Combustible Solids

wgk

WGK 3



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