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SML2190

BRD5529

≥98% (HPLC)

Synonym(s):

2-[4′-(Aminocarbonyl)[1,4′-bipiperidin]-1′-yl]-5-[(4-methylbenzoyl)amino]-3-pyridinecarboxylic acid

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$142.00
$120.70
25 mg

Available to ship TODAYfromMILWAUKEE

$566.00

About This Item

Empirical Formula (Hill Notation):
C25H31N5O4
CAS Number:
Molecular Weight:
465.54
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$120.70

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CC1=CC=C(C(NC2=CC(C(O)=O)=C(N3CCC(N4CCCCC4)(C(N)=O)CC3)N=C2)=O)C=C1

InChI

1S/C25H31N5O4/c1-17-5-7-18(8-6-17)22(31)28-19-15-20(23(32)33)21(27-16-19)29-13-9-25(10-14-29,24(26)34)30-11-3-2-4-12-30/h5-8,15-16H,2-4,9-14H2,1H3,(H2,26,34)(H,28,31)(H,32,33)

InChI key

ZXWHESBABUHJBE-UHFFFAOYSA-N

Biochem/physiol Actions

BRD5529 is a cell penetrant inhibitor of CARD9-TRIM62 interaction that binds to wt CARD9, preventing TRIM62 binding and ensuing inflammation. BRD5529 binding to CARD9 results in decrease ubiquitination.
Cell penetrant inhibitor of CARD9-TRIM62 interaction

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This Item
SML0453T7665SML2340
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98%

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98%

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 5 mg/mL (clear solution; warmed)

solubility

DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

-

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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