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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Please contact Customer Service for Availability | $399.00 $339.15 |
About This Item
Empirical Formula (Hill Notation):
C17H24N4O2S2
CAS Number:
Molecular Weight:
380.53
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
$339.15
List Price$399.00Save 15%Web-Only Promotion
Please contact Customer Service for Availability
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL
storage temp.
−20°C
SMILES string
O=C(NC1=NC=C(SCC2=NC=C(C(C)(C)C)O2)S1)C3CCNCC3
InChI
1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)
InChI key
OUSFTKFNBAZUKL-UHFFFAOYSA-N
Biochem/physiol Actions
SNS-032 (BMS-387032) is a selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9 that regulate the cell cycle and transcription. It has IC50 values of 38 nM for Cdk2, 62 nM for Cdk7, and 4 nM for Cdk9. SNS-032 was in clinical trials for a variety of cancers including chronic lymphocytic leukemia (CLL) and multiple myeloma (MM).
Selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 20 mg/mL, clear | solubility DMSO: >20 mg/mL |
| color white to beige | color white to beige | color white to beige | color off-white to tan |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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