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SML2301

EpoY

≥97% (HPLC), Vasohibin/SVBP inhibitor, powder

Synonym(s):

(2S,3S)-3-[[[(1S)-1-Carboxy-2-(4-hydroxyphenyl)ethyl]amino]carbonyl]-2-oxiranecarboxylic acid 2-ethyl ester, (S)-2-((2S,3S)-3-(ethoxycarbonyl) oxirane -2-carboxamido)-3-(4-hydroxyphenyl) propanoic acid, SD-142

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$110.00
25 mg

Available to ship TODAYfromMILWAUKEE

$443.00

About This Item

Empirical Formula (Hill Notation):
C15H17NO7
CAS Number:
Molecular Weight:
323.30
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥97% (HPLC)
Form:
powder

$110.00


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Product Name

EpoY, ≥97% (HPLC)

assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)[C@H]2O[C@@H]2C(OCC)=O

InChI

1S/C15H17NO7/c1-2-22-15(21)12-11(23-12)13(18)16-10(14(19)20)7-8-3-5-9(17)6-4-8/h3-6,10-12,17H,2,7H2,1H3,(H,16,18)(H,19,20)/t10-,11-,12-/m0/s1

InChI key

PSLWNPKMALERSK-SRVKXCTJSA-N

Biochem/physiol Actions

EpoY is an irreversible inhibitor of the major brain tubulin tyrosine carboxypeptidase (TCP), shown to be a complex of vasohibin-1 (VASH1) with the small vasohibin binding protein (SVBP). Reversible detyrosination of alpha-tubulin is vital to microtubule dynamics and functions including regulation of neuron differentiation, and defects in the detryosination have also been been associated with cancer and cardiomyopathies EpoY inhibited TCP activity with an IC50 value around 500 nM. It reduced detyrosinated a-tubulin levels and caused severe differentiation defects.
Inhibitor of Vasohibin/SVBP, a tubulin tyrosine carboxypeptidase (TCP) that regulates neuron differentiation.

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SBP3501071HPA000653
description

≥97% (HPLC)

description

-

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

assay

≥97% (HPLC)

assay

-

assay

-

form

powder

form

liquid

form

buffered aqueous glycerol solution

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

color

white to beige

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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