Skip to Content
MilliporeSigma

Skip To

SML2440

SGC-iMLLT

≥98% (HPLC)

Synonym(s):

(S)-1-Methyl-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazol-5-yl)-1H-indazole-5-carboxamide, Chemical Probe 92

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Check Cart for Availability
$91.10

About This Item

Empirical Formula (Hill Notation):
C22H24N6O
CAS Number:
Molecular Weight:
388.47
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$91.10


Check Cart for Availability

Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL

storage temp.

2-8°C

SMILES string

O=C(C1=CC2=C(N(C)N=C2)C=C1)NC3=CC=C4NC(CN5[C@@H](C)CCC5)=NC4=C3

InChI

1S/C22H24N6O/c1-14-4-3-9-28(14)13-21-25-18-7-6-17(11-19(18)26-21)24-22(29)15-5-8-20-16(10-15)12-23-27(20)2/h5-8,10-12,14H,3-4,9,13H2,1-2H3,(H,24,29)(H,25,26)/t14-/m0/s1

InChI key

QGNDVASWIHEXCL-AWEZNQCLSA-N

Biochem/physiol Actions

SGC-iMLLT (Chemical Probe 92) is a cell penetrant, potent and selective inhibitor of YEATS domain MLLT1/3 histone interaction. SGC-iMLLT downregulates MYC and DDN genes, while increases CD86 in MV4;11 AML cells.
cell penetrant, potent and selective inhibitor of YEATS domain MLLT1/3 histone interaction

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
SML1984SML2826SML1985
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige

Chemical Probe 92 SGC-iMLLT

-

-

(R)-N-(1,3-Dimethyl-6-(2-methylpiperazin-1-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl) chemical probe, BRPF1 inhibitor GSK6853, GSK6853 bioactive small molecule for labs, GSK6853 bromodomain inhibitor, GSK6853 chemical probe high purity, GSK6853 epigenetic chemical probe, GSK6853 for cellular efficacy in mice, GSK6853 for in vivo studies, GSK6853 inhibitor for BRPF1 targeting, GSK6853 pharmacokinetic properties research, GSK6853 research chemical for epigenetics, N-[2,3-Dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2 lab-grade, high-affinity GSK6853 for cellular efficacy, structural genomics SGC GSK6853 probe


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters