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SML2469

Oxanthroquinone G01

≥98% (HPLC)

Synonym(s):

9,10-Dihydro-8-hydroxy-3-methoxy-1,7-dimethyl-9,10-dioxo-2-anthracenecarboxylic acid ethyl ester, G01

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Size/SKUAvailabilityPrice
5 mg
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$91.10
$77.43

About This Item

Empirical Formula (Hill Notation):
C20H18O6
CAS Number:
Molecular Weight:
354.35
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$77.43

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assay

≥98% (HPLC)

form

powder

color

faint yellow to dark orange

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1C2=C(C=C(OC)C(C(OCC)=O)=C2C)C(C3=CC=C(C)C(O)=C31)=O

InChI

1S/C20H18O6/c1-5-26-20(24)15-10(3)14-12(8-13(15)25-4)18(22)11-7-6-9(2)17(21)16(11)19(14)23/h6-8,21H,5H2,1-4H3

InChI key

NWSATONEZZIFDE-UHFFFAOYSA-N

Biochem/physiol Actions

Oxanthroquinone G01 is a potent inhibitor of KRAS and NRAS plasma membrane localization that potently inhibits proliferation of KRAS transformed cancer cells. Oxanthroquinone G01 also inhibits recycling of epidermal growth factor receptor and transferrin receptor, but has no influence on cholera toxin internalization. It also increases cellular levels of sphingomyelin and and ceramide.
potent inhibitor of KRAS and NRAS plasma membrane localization, putative RAS inhibitor

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SML1887SML1854SML0684
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

H2O: 3 mg/mL, clear (warmed)

solubility

DMSO: 10 mg/mL, clear

color

faint yellow to dark orange

color

white to beige

color

blue

color

, light pink to red to very dark purple


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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