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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $91.10 $94.40 |
About This Item
Empirical Formula (Hill Notation):
C20H18O6
CAS Number:
Molecular Weight:
354.35
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
$94.40
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Available to ship TODAYDetails
assay
≥98% (HPLC)
form
powder
color
faint yellow to dark orange
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C1C2=C(C=C(OC)C(C(OCC)=O)=C2C)C(C3=CC=C(C)C(O)=C31)=O
InChI
1S/C20H18O6/c1-5-26-20(24)15-10(3)14-12(8-13(15)25-4)18(22)11-7-6-9(2)17(21)16(11)19(14)23/h6-8,21H,5H2,1-4H3
InChI key
NWSATONEZZIFDE-UHFFFAOYSA-N
Biochem/physiol Actions
Oxanthroquinone G01 is a potent inhibitor of KRAS and NRAS plasma membrane localization that potently inhibits proliferation of KRAS transformed cancer cells. Oxanthroquinone G01 also inhibits recycling of epidermal growth factor receptor and transferrin receptor, but has no influence on cholera toxin internalization. It also increases cellular levels of sphingomyelin and and ceramide.
potent inhibitor of KRAS and NRAS plasma membrane localization, putative RAS inhibitor
1 of 1
This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description targeting mouse NRAS | description clone 234-4.2, from mouse |
| assay ≥98% (HPLC) | assay - | assay - |
| form powder | form lyophilized, lyophilized powder | form - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - |
| color faint yellow to dark orange | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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