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SML2541

JWG-071

≥98% (HPLC)

Synonym(s):

11-(sec-butyl)-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)phenyl)amino)-5-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one, 5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-methyl-11-(1-methylpropyl)-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onAugust 17, 2026fromMILWAUKEE

$129.00
25 mg

Estimated to ship onAugust 17, 2026fromMILWAUKEE

$420.00
$357.00

About This Item

Empirical Formula (Hill Notation):
C34H44N8O3
CAS Number:
Molecular Weight:
612.76
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$129.00


Estimated to ship onAugust 17, 2026Details


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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N6(CCN(CC6)C)C1CCN(CC1)C(=O)c2cc(c(cc2)Nc3nc4[n](c5c([c]([n](c4cn3)C)=O)cccc5)C(CC)C)OC

InChI

1S/C34H44N8O3/c1-6-23(2)42-28-10-8-7-9-26(28)33(44)39(4)29-22-35-34(37-31(29)42)36-27-12-11-24(21-30(27)45-5)32(43)41-15-13-25(14-16-41)40-19-17-38(3)18-20-40/h7-12,21-23,25H,6,13-20H2,1-5H3,(H,35,36,37)

InChI key

ACWOMSOYIIVIRV-UHFFFAOYSA-N

Biochem/physiol Actions

JWG-071 is a selective inhibitor of ERK5 (MAPK7) and LRRK2 with an IC50 value of 88nM for ERK5 inhibition and 109 nM for LRRK2 inhibition.
Selective ERK5 (MAPK7) Inhibitor

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This Item
SML2080SML1753SML2568
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

orange to brown

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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