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SML2547

KCC-07

≥98% (HPLC)

Synonym(s):

3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol

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5 mg

Available to ship TODAYfromMILWAUKEE

$117.00
25 mg
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$470.00

About This Item

Empirical Formula (Hill Notation):
C14H11N3OS
CAS Number:
Molecular Weight:
269.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$117.00


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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=CC(NC2=NC(C3=NC=CC=C3)=CS2)=CC=C1

InChI key

GIGNWEDIMLUWCT-UHFFFAOYSA-N

Biochem/physiol Actions

KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. KCC-07 inhibits medulloblastoma cell proliferation, and inhibits tumor growth in mice xenograft models of medulloblastoma.
brain penetrant, potent and selective inhibitor of MBD2 that inducing anti-proliferative BAI1/p53/p21 signaling

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vibrant-m

IC-07

description

≥98% (HPLC)

description

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA., Reactivity: Anti-Galactocerebroside, chicken, no DNA, 93062301

assay

≥98% (HPLC)

assay

-

form

powder

form

-

storage temp.

2-8°C

storage temp.

−196°C

solubility

DMSO: 2 mg/mL, clear

solubility

-

color

white to beige

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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