SML2547
KCC-07
≥98% (HPLC)
Synonym(s):
3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $113.00 $96.05 |
25 mg | Check Cart for Availability | $454.00 |
About This Item
Empirical Formula (Hill Notation):
C14H11N3OS
CAS Number:
Molecular Weight:
269.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
$96.05
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Available to ship TODAYDetails
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC(NC2=NC(C3=NC=CC=C3)=CS2)=CC=C1
InChI key
GIGNWEDIMLUWCT-UHFFFAOYSA-N
Biochem/physiol Actions
KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. KCC-07 inhibits medulloblastoma cell proliferation, and inhibits tumor growth in mice xenograft models of medulloblastoma.
brain penetrant, potent and selective inhibitor of MBD2 that inducing anti-proliferative BAI1/p53/p21 signaling
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description >98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay >98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 5 mg/mL, clear (warmed) | solubility DMSO: 15 mg/mL, clear | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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