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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $71.00 |
25 mg | Check Cart for Availability | $230.00 |
About This Item
Empirical Formula (Hill Notation):
C16H13N5
CAS Number:
Molecular Weight:
275.31
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
C#CCNC1=NC=CC(C2=CC=C(N3C=NC=C3)C=C2)=N1
InChI
1S/C16H13N5/c1-2-8-18-16-19-9-7-15(20-16)13-3-5-14(6-4-13)21-11-10-17-12-21/h1,3-7,9-12H,8H2,(H,18,19,20)
InChI key
QKHQFSQJQKGFAA-UHFFFAOYSA-N
Biochem/physiol Actions
AP-C5 is a potent and selective inhibitor of the guanosine 3′,5′-cyclicmonophosphate (cGMP)-dependent protein kinase II (cGKII)that selectively blocks cGKII dependent phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) in intestinal organoids. AP-C5 mitigates secretory response provoked by the GCC-activating Escherichia coli heat-stable toxin (STa) in mouse small intestinal tissue.
potent and selective inhibitor of the guanosine 3′,5′-cyclicmonophosphate (cGMP)-dependent protein kinase II (cGKII)
1 of 1
This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | description Pharmaceutical Secondary Standard; Certified Reference Material |
| assay ≥98% (HPLC) | assay - | assay - |
| form powder | form buffered aqueous glycerol solution | form - |
| Quality Level 100 | Quality Level 100 | Quality Level 300 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - |
| color white to beige | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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