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SML2560

OB-1

≥98% (HPLC)

Synonym(s):

Ethyl 5-(1-methyl-4-nitro-1H-imidazol-5-yloxy)-2-phenylbenzofuran-3-carboxylate

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5 mg
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$91.10
$77.43
25 mg

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$296.00

About This Item

Empirical Formula (Hill Notation):
C21H17N3O6
CAS Number:
Molecular Weight:
407.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$77.43

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assay

≥98% (HPLC)

form

powder

color

white to very dark brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[N+](=O)([O-])c1nc[n](c1Oc2cc3c([o]c(c3C(=O)OCC)c4ccccc4)cc2)C

InChI key

UJHGRDVYTTVJFD-UHFFFAOYSA-N

Biochem/physiol Actions

Inhibitor of Stomatin-like protein-3 (STOML3) oligomerization
OB-1 is an inhibitor of the oligomerization of Stomatin-like protein-3 (STOML3), which is a modulator of the mechanosensitive ion channel Piezo2. STOML3 requires oligomerization for its role as an endogenous regulator of the sensitivity of mechanosensitive Piezo ion channels in sensory neurons. By inhibiting this activity, OB-1 has been shown to reduce touch-evoked pain behavior in two mouse models of neuropathic pain.

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This Item
SML2274SML1276SML0943
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

H2O: 2 mg/mL, clear (warmed)

color

white to very dark brown

color

white to beige

color

white to beige

color

orange to dark red


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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