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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $91.10 $77.43 |
25 mg | Available to ship TODAYfromMILWAUKEE | $296.00 |
About This Item
Empirical Formula (Hill Notation):
C21H17N3O6
CAS Number:
Molecular Weight:
407.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
$77.43
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assay
≥98% (HPLC)
form
powder
color
white to very dark brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[N+](=O)([O-])c1nc[n](c1Oc2cc3c([o]c(c3C(=O)OCC)c4ccccc4)cc2)C
InChI key
UJHGRDVYTTVJFD-UHFFFAOYSA-N
Biochem/physiol Actions
Inhibitor of Stomatin-like protein-3 (STOML3) oligomerization
OB-1 is an inhibitor of the oligomerization of Stomatin-like protein-3 (STOML3), which is a modulator of the mechanosensitive ion channel Piezo2. STOML3 requires oligomerization for its role as an endogenous regulator of the sensitivity of mechanosensitive Piezo ion channels in sensory neurons. By inhibiting this activity, OB-1 has been shown to reduce touch-evoked pain behavior in two mouse models of neuropathic pain.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description - |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 10 mg/mL, clear | solubility H2O: 2 mg/mL, clear (warmed) |
| color white to very dark brown | color white to beige | color white to beige | color orange to dark red |
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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