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SML2642

S29434

≥98% (HPLC)

Synonym(s):

N-[2-(2-Methoxy-6H-dipyrido[2,3-a:3′,2′-e]pyrrolizin-11-yl)ethyl]-2-furancarboxamide, S 29434, [2-(2-methoxy-5H-1,4b,9-triaza(indeno[2,1-a]inden-10-yl)ethyl]-2-furamide

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$169.00
25 mg

Available to ship TODAYfromMILWAUKEE

$679.00

About This Item

Empirical Formula (Hill Notation):
C21H18N4O3
CAS Number:
Molecular Weight:
374.39
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$169.00


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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[n]21c3c(nc(cc3)OC)c(c2c5ncccc5C1)CCNC(=O)c4[o]ccc4

InChI

1S/C21H18N4O3/c1-27-17-7-6-15-19(24-17)14(8-10-23-21(26)16-5-3-11-28-16)20-18-13(12-25(15)20)4-2-9-22-18/h2-7,9,11H,8,10,12H2,1H3,(H,23,26)

InChI key

XJIUMLVQBQKCJA-UHFFFAOYSA-N

Biochem/physiol Actions

S29434 is a cell and blood-rain barrier penetrant, potent and selective inhibitor of quinone reductase 2 (QR2, NQO2) that inhibits production of ROS by QR2 in cells. S29434 triggers autophagy in human HepG2 cells. S29434 enhances exploring time of the unfamiliar object in mice memory test.
blood-brain barrier penetrant, potent and selective inhibitor of quinone reductase 2 (QR2)


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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