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SML2666

Diflapolin

≥98% (HPLC)

Synonym(s):

N-[4-(2-Benzothiazolylmethoxy)-2-methylphenyl]-N′-(3,4-dichlorophenyl)-urea, N-[4-(Benzothiazol-2-ylmethoxy)-2-methylphenyl]-N′-(3,4-dichlorophenyl)urea

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5 mg

Available to ship TODAYfromMILWAUKEE

$73.20
$62.22
25 mg

Available to ship TODAYfromMILWAUKEE

$296.00
$251.60

About This Item

Empirical Formula (Hill Notation):
C22H17Cl2N3O2S
CAS Number:
724453-98-9
Molecular Weight:
458.36
UNSPSC Code:
41116004
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(NC1=CC=C(Cl)C(Cl)=C1)NC2=C(C)C=C(OCC3=NC4=CC=CC=C4S3)C=C2

InChI

1S/C22H17Cl2N3O2S/c1-13-10-15(29-12-21-26-19-4-2-3-5-20(19)30-21)7-9-18(13)27-22(28)25-14-6-8-16(23)17(24)11-14/h2-11H,12H2,1H3,(H2,25,27,28)

InChI key

FGXLEECGXSDIMM-UHFFFAOYSA-N

Biochem/physiol Actions

Diflapolin is a bioavailable, highly potent and highly selective dual FLAP/sEH (5-LO-activating protein/ soluble epoxide hydrolase) inhibitor that suppresses leukotriene formation and increases epoxyeicosatrienoic acids levels. Diflapolin exhibit potent anti-inflammatory activities in mice models.
bioavailable, highly potent and highly selective dual FLAP/sEH (5-LO-activating protein/ soluble epoxide hydrolase) inhibitor

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Diflapolin ≥98% (HPLC)

Sigma-Aldrich

SML2666

Diflapolin

YM 022 ≥98% (HPLC)

Sigma-Aldrich

SML0220

YM 022

Fenobam ≥98% (HPLC), solid

Sigma-Aldrich

F0430

Fenobam

SB-408124 ≥98% (HPLC), solid

Sigma-Aldrich

S2694

SB-408124

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC), solid

description

≥98% (HPLC), solid

form

powder

form

powder

form

solid

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 5 mg/mL (clear solution)

solubility

DMSO: >20 mg/mL

solubility

DMSO: >10 mg/mL

color

white to beige

color

white to beige

color

white

color

off-white

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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