SML2680
ES24
≥98% (HPLC)
Synonym(s):
2-{2-[3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazino}-2-oxoethylbenzene
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $94.40 |
25 mg | Available to ship TODAYfromMILWAUKEE | $307.00 |
About This Item
Empirical Formula (Hill Notation):
C15H13N3O4
Molecular Weight:
299.28
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
faint yellow to dark orange
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Biochem/physiol Actions
ES24 is an Eeyarestatin 1 analog that blocks protein translocation in vitro and more effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER). Apparently ES24 keep Sec61 in open position allowing Ca2+ ions to move freely through the aqueous channel present. It causes cell-type-specific Ca2+-dependent cell death.
blocks protein translocation in vitro and effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER).
1 of 1
This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description - | description mol wt 25,000-40,000 |
| assay ≥98% (HPLC) | assay - | assay - |
| form powder | form buffered aqueous solution | form powder or solid |
| Quality Level 100 | Quality Level 100 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - |
| color faint yellow to dark orange | color - | color white to faint yellow |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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