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SML2741

Sultopride hydrochloride

≥98% (HPLC)

Synonym(s):

(±)-Sultopride HCl, LIN 1418 HCl, LIN1418 HCl, N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride, N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-o-anisamide monohydrochloride

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Size/SKUAvailabilityPrice
10 mg
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$91.10
50 mg
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$296.00

About This Item

Empirical Formula (Hill Notation):
C17H26N2O4S·HCl
CAS Number:
Molecular Weight:
390.93
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

$91.10


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

[S](=O)(=O)(CC)c1cc(c(cc1)OC)C(=O)NCC2[N+H](CCC2)CC.[Cl-]

InChI

1S/C17H26N2O4S.ClH/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3;/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20);1H

InChI key

IGOWMQPOGQYFFM-UHFFFAOYSA-N

Biochem/physiol Actions

Orally active benzamide class dopamine receptor D2/3-selective antagonist (Ki = 18 nM/D2, 22 nM/D3, 7.7 μM/D4, >10 μM/D1) with in vivo antipsychotic efficacy.
Sultopride is an orally active benzamide class dopamine receptor D2/3-selective antagonist (Ki = 18 nM/rat D2, 22 nM/human D3, 7.7 μM/human D4, >10 μM/rat D1 by competitive binding against 0.5 nM Spiperone, 0.2 nM YM-09151-2, 5 nM Spiperone, 0.2 nM SCH23390 for respective receptor) that displays in vivo antipsychotic efficacy with moderate atypical index. Sultopride exhibits little or no affinity toward 5-HT1A2/33, adrenaline receptor α12, Ach receptor, histamine receptor H1, or Sigma receptors σ12. Sultopride is a racemic material composed of the highly active (-) and the less potent (+) enenatiomers.

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This Item
S8010E101S7771
description

≥98% (HPLC)

description

-

description

≥98% (HPLC), powder

description

≥98% (titration)

form

powder

form

powder

form

powder

form

-

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

assay

≥98% (titration)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

solubility

H2O: 2 mg/mL, clear

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL, 0.1 M HCl: soluble, H2O: slightly soluble, ethanol: soluble

solubility

H2O: soluble >10 mg/mL, ethanol: soluble 2.6 mg/mL, 0.1 M HCl: soluble 7 mg/mL

solubility

-

storage condition

desiccated

storage condition

-

storage condition

desiccated

storage condition

-


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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