Skip to Content
MilliporeSigma

Skip To

SML2782

Br-PBTC

≥98% (HPLC)

Synonym(s):

(R)-7-Bromo-N-(piperidin-3-yl)benzo[b]thiophene-2-carboxamide, 7-Bromo-N-(3R)-3-piperidinylbenzo[b]thiophene-2-carboxamide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$88.20
$74.97
25 mg

Available to ship TODAYfromMILWAUKEE

$357.00
$303.45

About This Item

Empirical Formula (Hill Notation):
C14H15BrN2OS
CAS Number:
Molecular Weight:
339.25
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$74.97

List Price$88.20Save 15%
Web-Only Promotion

Available to ship TODAYDetails


Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1=CC(C=CC=C2Br)=C2S1)N[C@@H]3CCCNC3

InChI

1S/C14H15BrN2OS/c15-11-5-1-3-9-7-12(19-13(9)11)14(18)17-10-4-2-6-16-8-10/h1,3,5,7,10,16H,2,4,6,8H2,(H,17,18)/t10-/m1/s1

InChI key

LRYYPTVUWGMZQB-SNVBAGLBSA-N

Biochem/physiol Actions

Br-PBTC is a selective and potent type II positive allosteric modulator (PAM) that potentiates the opening of the nicotinic acetylcholine receptors (nAChR) subtypes containing α4β2, α2β2 and α2β4 subunits. Br-PBTC potentiates opening and reactivates desensitized (α4β2)2α4 nAChRs. It appears that Br-PBTC interacts with extracellular C-terminus of α2 or α4 in association with nearby parts of the α subunit.
selective and potent type II PAM that potentiates the opening of the nAChR subtypes containing α4β2, α2β2 and α2β4 subunits.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
SML1432SML1865T1452
description

≥98% (HPLC)

description

≥97% (HPLC)

description

≥98% (HPLC)

description

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 1 mg/mL, clear (warmed)

solubility

DMSO: 5 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to light brown


Storage Class

11 - Combustible Solids

wgk

WGK 3



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

Reviews

No rating value

Active Filters