SML2798
CH625
≥98% (HPLC)
Synonym(s):
(2E)-1-(4-Hydroxy-2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 4,4′-Dihydroxy-2′,6′-dimethoxychalcone, ZINC95910725
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $73.10 |
25 mg | Available to ship TODAYfromMILWAUKEE | $298.00 |
About This Item
Empirical Formula (Hill Notation):
C17H16O5
CAS Number:
Molecular Weight:
300.31
NACRES:
NA.77
UNSPSC Code:
51111800
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
CH625 is a potent and selective competitive inhibitor of CYP4X1 that decreases tumor burden, increases survival in glioma intracranial and subcutaneous model in rats. CH625 normalizes tumor vasculature in the C6 and GL261 gliomas through tumor-associated macrophages (TAMs) reprograming and inhibition of VEGF and TGF-β production.
potent and selective competitive inhibitor of CYP4X1 that decreases tumor burden, increases survival in gliomas
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description AldrichCPR | description AldrichCPR | description AldrichCPR |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| form powder | form solid | form solid | form solid |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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