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SML2810

Prostetin Trifluoroacetic acid salt

≥98% (HPLC), MAP4K inhibitor, powder

Synonym(s):

2-(4-(4-(3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)piperazin-1-yl)ethan-1-ol Trifluoroacetic acid salt, 2-(4-(4-(3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzyl)piperazin-1-yl)ethanol Trifluoroacetic acid salt, 4-[[4-[3-(3-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]phenyl]methyl]-1-piperazineethanol Trifluoroacetic acid salt

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Size/SKUAvailabilityPrice
5 mg
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$170.00
$144.50
25 mg
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$657.00

About This Item

Empirical Formula (Hill Notation):
C26H27ClN4O · xC2HF3O2
Molecular Weight:
446.97 (free base basis)
UNSPSC Code:
12352106
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$144.50

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Product Name

Prostetin Trifluoroacetic acid salt, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

Prostetin is an orally available, blood-brain barrier-penetrant, potent and metabolically stable inhibitor of the mitogen-activated protein kinase kinase kinase kinase (MAP4K, or HGK) that exhibits neuroprotective and anti-inflammatory properties. Prostetin is more potent than URMC-099 in motor neuron survival assay. Prostetin rescues CPA-induced neurodegeneration in motor neurons.
orally available, blood-brain barrier-penetrant, potent and metabolically stable inhibitor of MAP4K (HGK) that exhibits neuroprotective properties

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This Item
SML1145SML2384SML0773
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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