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SML2861

FIT-039

≥98% (HPLC)

Synonym(s):

FIT 039, FIT039, N-(5-Fluoro-2-(piperidin-1-yl)phenyl)pyridine-4-carbothioamide, N-[5-Fluoro-2-(1-piperidinyl)phenyl]-4-pyridinecarbothioamide

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$73.10
25 mg

Available to ship TODAYfromMILWAUKEE

$298.00

About This Item

Empirical Formula (Hill Notation):
C17H18FN3S
CAS Number:
Molecular Weight:
315.41
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$73.10


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

Fc1cc(c(cc1)N3CCCCC3)NC(=S)c2ccncc2

InChI key

VRKZHYSJZOUICG-UHFFFAOYSA-N

Biochem/physiol Actions

FIT-039 is a potent and selective cyclin-dependent kinase 9 (CDK9) inhibitor that binds to the ATP -binding pocket of CDK9 and inhibits the kinase activity of P-TEFb complex. FIT-039 inhibits replication of herpes simplex virus 1 (HSV-1), HSV-2, human adenovirus, and human cytomegalovirus in cultured cells. FIT-039 ointment inhibits formation of skin legion in a mice HSV-1 infection model.
potent and selective cyclin-dependent kinase 9 (CDK9) inhibitor; antiviral agent

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assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

-

form

powder

form

powder

form

-

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

300

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

storage temp.

-

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

color

white to beige

color

faint yellow to dark orange

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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