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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | $122.00 $103.70 |
25 mg | Please contact Customer Service for Availability | $396.00 $336.60 |
About This Item
Empirical Formula (Hill Notation):
C14H12N4OS · 2HCl
CAS Number:
Molecular Weight:
357.26
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
$103.70
List Price$122.00Save 15%Web-Only Promotion
Please contact Customer Service for Availability
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC1=NC(C2=C(N1)C=CC(C)=C2SC3=CC=NC=C3)=O
InChI
1S/C14H12N4OS.2ClH/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9;;/h2-7H,1H3,(H3,15,17,18,19);2*1H
InChI key
PJKVJJYMWOCLIJ-UHFFFAOYSA-N
Biochem/physiol Actions
Nolatrexed dihydrochloride is a water-soluble lipophilic quinazoline folate analog that exhibits potent antineoplastic activity. Nolatrexed is a potent thymidylate synthase inhibitor that inhibits thymine synthesis followed by inhibition of DNA replication.
potent thymidylate synthase inhibitor
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: 2 mg/mL, clear | solubility H2O: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility H2O: ≥5 mg/mL at warmed |
| storage condition desiccated | storage condition desiccated | storage condition desiccated | storage condition desiccated |
signalword
Warning
hcodes
Hazard Classifications
Muta. 2 - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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