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SML2950

E7820

≥98% (HPLC)

Synonym(s):

3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide, 3-Cyano-N-(3-cyano-4-methyl-1H-indole-7-yl)benzensulfonamide, E 7820, NSC 719239

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onAugust 17, 2026fromMILWAUKEE

$88.20
$74.97
25 mg

Estimated to ship onAugust 17, 2026fromMILWAUKEE

$288.00
$244.80

About This Item

Empirical Formula (Hill Notation):
C17H12N4O2S
CAS Number:
Molecular Weight:
336.37
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$74.97

List Price$88.20Save 15%
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Estimated to ship onAugust 17, 2026Details


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ligand

E7820

Quality Segment

assay

≥98% (HPLC)

form

powder

reaction suitability

reagent type: ligand

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(Nc2c3[nH]cc(c3c(cc2)C)C#N)c1cc(ccc1)C#N

InChI

1S/C17H12N4O2S/c1-11-5-6-15(17-16(11)13(9-19)10-20-17)21-24(22,23)14-4-2-3-12(7-14)8-18/h2-7,10,20-21H,1H3

InChI key

LWGUASZLXHYWIV-UHFFFAOYSA-N

Biochem/physiol Actions

E7820 (NSC 719239) is an orally available anticancer and antiangiogenic agent that inhibits VEGF-2 or FGF-2-induced tube formation of HUVEC cells through the suppression of integrin α2. E7820 promotes selective proteasomal degradation of the U2AF-related splicing factor CAPERα (coactivator of activating protein-1 and estrogen receptors) by ubiquitination and degradation via CRL4DCAF15.
inducer of selective proteasomal degradation of CAPERα

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This Item
S3445SML0421SML1225
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: ≥20 mg/mL, H2O: ≥20 mg/mL

solubility

DMSO: 15 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

color

white to beige

color

off-white to light brown

color

white to light brown

color

white to pink


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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