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SML2963

8-Azaguanine

≥98% (HPLC)

Synonym(s):

5-Amino-1H-v-triazolo[d]pyrimidin-7-ol, 5-Amino-3,6-dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one, 5-Amino-7-hydroxy-1H-v-triazolo[d]pyrimidine, 8-AG, Guanazolo, NSC 151069, NSC 223526, pathocidin, 2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$63.90
50 mg

Available to ship TODAYfromMILWAUKEE

$247.00

About This Item

Empirical Formula (Hill Notation):
C4H4N6O
CAS Number:
Molecular Weight:
152.11
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
171098
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder

$63.90


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

mp

>300 °C (lit.)

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

NC1=Nc2[nH]nnc2C(=O)N1

InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

InChI key

LPXQRXLUHJKZIE-UHFFFAOYSA-N

Biochem/physiol Actions

8-Azaguanine is a triazole-antimetabolite that displays varies pharmacological effects including anticancer, antiviral and antifungal. It is easily incorporated into ribonucleic acids including rRNA and tRNA. 8-Azaguanine appears to alter mRNA splicing in SF3B1 mutant cells. 8-Azaguanine novel immunomodulatory drug (IMiD) that significantly increases the cytotoxicity of NK cells.

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This Item
SML1214SML0273PZ0407
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥97% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: ≥5 mg/mL

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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