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SML2968

JA2131

≥98% (HPLC)

Synonym(s):

1,3,6,9-Tetrahydro-1,3-dimethyl-8-[[2-(4-morpholinyl)ethyl]thio]-6-thioxo-2H-purin-2-one, NSC 98003, NSC98003

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onAugust 03, 2026fromMILWAUKEE

$144.00
25 mg

Estimated to ship onAugust 03, 2026fromMILWAUKEE

$577.00

About This Item

Empirical Formula (Hill Notation):
C13H19N5O2S2
CAS Number:
Molecular Weight:
341.45
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$144.00


Estimated to ship onAugust 03, 2026Details


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

S(CCN3CCOCC3)c1[nH]c2c(n1)N(C(=O)N(C2=S)C)C

InChI

1S/C13H19N5O2S2/c1-16-10-9(11(21)17(2)13(16)19)14-12(15-10)22-8-5-18-3-6-20-7-4-18/h3-8H2,1-2H3,(H,14,15)

InChI key

XHNSOGDMSSHQFY-UHFFFAOYSA-N

Biochem/physiol Actions

JA2131 is a cell penetrant, potent and selective poly(ADP-ribose) glycohydrolase (PARG) inhibitor that selectively kills cancer cells. JA2131 induces PARP1 hyper-PARylation and sensitizes cancer cells to radiation-induced DNA damage. JA2131 induces replication fork defects.
cell penetrant, potent and selective poly(ADP-ribose) glycohydrolase (PARG) inhibitor

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This Item
SML3222SML2985SML0187
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: ≥10 mg/mL

color

white to beige

color

white to beige

color

white to beige

color

white to tan


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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