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SML2980

G6PDi-1

≥98% (HPLC), G6PD inhibitor, powder

Synonym(s):

4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile

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Size/SKUAvailabilityPrice
5 mg
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$105.00
25 mg
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$420.00

About This Item

Empirical Formula (Hill Notation):
C14H12N4OS
CAS Number:
Molecular Weight:
284.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$105.00


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Product Name

G6PDi-1, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1

InChI

1S/C14H12N4OS/c15-6-10-5-9(8-20-10)17-14-16-7-11-12(18-14)3-1-2-4-13(11)19/h5,7-8H,1-4H2,(H,16,17,18)

InChI key

USWCHVCZOGGQQA-UHFFFAOYSA-N

Biochem/physiol Actions

G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.
cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD)

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This Item
SML3322SML3062SML2945
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

, White to very dark grey

color

white to beige

color

white to brown


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. Una vez resuspendido en DMSO (5 mM), ¿cuánto tiempo es estable el producto?

    1 answer
    1. Solution stability of this product in DMSO has not been determined. However, other sources state that this compound is stable for 1 month at -20°C in DMSO. Note that this information has not been validated.

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