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SML3125

LEI-401

≥98% (HPLC)

Synonym(s):

N-(Cyclopropylmethyl)-6-((S)-3-hydroxypyrrolidin-1-yl)-2-((S)-3-phenylpiperidin-1-yl)pyrimidine-4-carboxamide, N-(Cyclopropylmethyl)-6-[(3S)-3-hydroxy-1-pyrrolidinyl]-2-[(3S)-3-phenyl-1-piperidinyl]-4-pyrimidinecarboxamide

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$208.00
25 mg

Available to ship TODAYfromMILWAUKEE

$833.00

About This Item

Empirical Formula (Hill Notation):
C24H31N5O2
CAS Number:
Molecular Weight:
421.54
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$208.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1=CC(N2CC[C@@H](C2)O)=NC(N3CCC[C@H](C3)C4=CC=CC=C4)=N1)NCC5CC5

InChI

1S/C24H31N5O2/c30-20-10-12-28(16-20)22-13-21(23(31)25-14-17-8-9-17)26-24(27-22)29-11-4-7-19(15-29)18-5-2-1-3-6-18/h1-3,5-6,13,17,19-20,30H,4,7-12,14-16H2,(H,25,31)/t19-,20+/m1/s1

InChI key

GFHJYPQZBBHOCC-UXHICEINSA-N

Biochem/physiol Actions

CNS-active, potent and selective inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD)
LEI-401 is a CNS-active, potent and selective inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD). LEI-401 reduces N-acylethanolamines (NAEs) in in the brain of freely moving mice and neuroblastoma cells.

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This Item
SML1249SML3129SML3550
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥95% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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