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SML3189

BMS-265246

≥98% (HPLC)

Synonym(s):

(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone, BMS 265246, BMS265246

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$161.00
25 mg

Available to ship TODAYfromMILWAUKEE

$515.00

About This Item

Empirical Formula (Hill Notation):
C18H17F2N3O2
CAS Number:
Molecular Weight:
345.34
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$161.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

FC1=C(C(F)=CC(C)=C1)C(C2=C(C3=C(N=C2)NN=C3)OCCCC)=O

InChI

1S/C18H17F2N3O2/c1-3-4-5-25-17-11(8-21-18-12(17)9-22-23-18)16(24)15-13(19)6-10(2)7-14(15)20/h6-9H,3-5H2,1-2H3,(H,21,22,23)

InChI key

SCFMWQIQBVZOQR-UHFFFAOYSA-N

Biochem/physiol Actions

ATP site-targeting, potent and CDK1/CDK2-selective cyclin-dependent kinase inhibitor with anti-cancer efficacy in A2780 ovarian cancer culture.
BMS-265246 is an ATP site-targeting, potent and CDK1/2-selective cyclin-dependent kinase inhibitor (IC50 = 6 nM/CDK1, 9 nM/CDK2, 230 nM/CDK4) with anti-cancer efficacy in A2780 ovarian cancer culture (IC50 = 760 nM).

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This Item
SML3116SML0805SML1694
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 1 mg/mL, clear (warmed)

solubility

DMSO: 5 mg/mL, clear (warmed)

color

white to beige

color

white to gray

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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